The following are some of the common factors which can cause tablet capping.
Tablet capping and lamination.
Abstract air entrapment efficiency of the powders is one of the main factors leading to occurrence of capping or lamination tendency of tablets manufactured from the directly compressible powder blends.
This challenge can be overcome by doing a pre compression as well as reducing the compression and minimizing the tableting rate.
Lamination is also caused by the presence of a large amount of fines in the granulations.
Although the method is widely used there are still significant challenges with achieving a high quality compact.
Using acetaminophen containing formulations we examined the potential use of a compaction simulator as a material sparing tool to predict capping occurrence under commercial.
This is the problem faced in the formulation of the granules.
Tablet capping and lamination powder compaction is widely used to produce pharmaceutical tablets and is referred to as a tabletting process.
Fines are small dust particles which.
Lamination is whenever tablet is breaking or separating anywhere rather than top if is separating from top it is capping.
Machine related in this article we will be discussing five major causes of this problem and remedies for them.
First lamination is caused by air being trapped in the tablet especially among the granules or particles.
Better understand the tablet capping lamination phenomenon.